雪球网今日 2024年09月06日
$再生元制药(REGN)$ 肿瘤海外后发者想要逆袭只能靠头对头PK,正面击败先发者。LIBTAYO +Lag3 vs K+chemo,LIBTAYO +Lag3 vs Opdualag(O+Lag3)So we're excited...
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再生元制药在肿瘤领域寻求突破,采取了正面竞争的策略,计划将LIBTAYO与Lag3组合进行临床试验,与现有先发药物进行头对头比较,目标是超越现有治疗方案,在疗效和生存率方面取得显著优势。再生元制药计划与Keytruda进行对比试验,并与Bristol-Myers Squibb的Opdualag进行正面PK,最终目标是实现总体生存率的提升,并与现有药物区分开来。

🤔再生元制药肿瘤领域面临挑战:作为后发者,需要正面击败先发者才能取得突破。

💪再生元制药的策略:将LIBTAYO与Lag3组合进行临床试验,与现有先发药物进行头对头比较,目标是超越现有治疗方案。

🎯再生元制药的具体计划:与Keytruda进行对比试验,并与Bristol-Myers Squibb的Opdualag进行正面PK,最终目标是实现总体生存率的提升,并与现有药物区分开来。

📈再生元制药的期望:通过临床试验数据,证明LIBTAYO+Lag3组合在疗效和生存率方面优于现有药物,并最终实现肿瘤领域逆袭。

🚀再生元制药的未来:如果临床试验结果如预期,将为再生元制药在肿瘤领域带来新的突破,并为患者带来新的治疗希望。

🏆再生元制药的竞争优势:再生元制药通过头对头PK,正面击败先发者,展现了其强大的竞争实力和对肿瘤领域的信心。

来源:雪球App,作者: 张小丰,(https://xueqiu.com/9518372158/303849518)

$再生元制药(REGN)$ 肿瘤海外后发者想要逆袭只能靠头对头PK,正面击败先发者。LIBTAYO +Lag3 vs K+chemo,LIBTAYO +Lag3 vs Opdualag(O+Lag3)

So we're excited to see what the Phase III data looks like next year, which uses pembrolizumab as the control. So we'll be testing Inmazeb plus LIBTAYO versus pembro-monotherapy. We also have a head-to-head study underway that combines our Inmazeb LIBTAYO and compares it to Opdualag, the approved LAG-3 PD-1 combination from Bristol-Myers. That trial just got underway and we'll be enrolling -- we are enrolling now and hope to get data, I think in 2026.

The primary endpoint there is objective response rate. We'll also be evaluating PFS and OS. One thing that we're really hopeful for in the KEYTRUDA-controlled study is to achieve overall survival, which was an endpoint that Opdualag missed in its metastatic melanoma program. And really, I think is an important one that if we can demonstrate we'll differentiate us beyond just the head-to-head data we hope to generate.

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再生元制药 肿瘤 LIBTAYO Lag3 临床试验 头对头PK
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