Brian Deer在本次访谈中详述了他新书《欺骗世界的医生》的内容，揭露了Andrew Wakefield如何通过1998年《柳叶刀》杂志上的论文，错误地将MMR疫苗与自闭症联系起来，并探讨了这一事件背后的科学欺诈和反疫苗运动的兴起。

🔍 Brian Deer是一位屡获殊荣的调查记者，以其对制药行业的报道而闻名。他的新书《欺骗世界的医生》深入挖掘了Andrew Wakefield的研究背后的复杂故事。

📚 Andrew Wakefield的1998年《柳叶刀》论文声称MMR疫苗与自闭症有联系，但Brian揭露了这一研究是如何基于预先设定的信念而非科学证据。

🔬 Brian详细描述了研究过程中的幕后故事，包括实验室的问题和分析中的不一致之处，揭示了科学被议程驱动而非开放探究的危险。

🧪 Wakefield的研究存在许多缺陷，包括对儿童造成的伤害和未能进行特异性序列分析，这些都被Brian一一指出。

📉 Brian还揭露了伪造的PCR测试如何进一步推动了MMR疫苗导致自闭症的错误信念，并最终导致了《柳叶刀》论文的撤回和Wakefield执照的吊销。

Brian Deer is an award-winning investigative journalist best known for his coverage of the pharmaceutical industry. In this episode, he and Peter discuss the content of his book, The Doctor Who Fooled the World: Science, Deception, and the War on Vaccines, which exposes the complex and disturbing story behind the infamous 1998 Lancet paper by Andrew Wakefield linking the MMR vaccine and autism. Brian explains how doctors led by Wakefield, a lawyer, and an anti-vaccination parents’ group worked together on a study to validate their preconceived belief that the MMR vaccine caused autism. He reveals what happened behind the scenes as the study was carried out, explains problems in the lab, and discusses inconsistencies in the analysis.  In the end, this is a story that serves as a cautionary tale about the consequences of science driven by an agenda rather than by a spirit of open inquiry.

 

We discuss:

How Andrew Wakefield’s flawed approach to scientific research led to the belief that vaccines cause autism (3:25); The importance of following the scientific method, and how Wakefield twisted the science to link measles virus to Crohn’s disease (14:15); The backstory behind Andrew Wakefield’s infamous 1998 Lancet paper linking the MMR vaccine and autism (26:45); The many flaws and disturbing aspects of Wakefield’s study: suffering children and failure to do strain-specific sequencing (45:15); The epicenter of fraud: Bogus PCR testing furthering the belief that measles virus from the MMR vaccine caused autism (1:00:00); Additional issues that contaminated the study results (1:22:15); Discovering the misrepresented medical records for the kids involved in the study leading to the retraction of the Lancet paper and Wakefield losing his license (1:31:00); The resurgence of the anti-vaccination movement, Brian’s motivation to write the book, and parting thoughts (1:36:45); and More.

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