arXiv:2507.15958v1 Announce Type: cross Abstract: Accurate and efficient skin lesion classification on edge devices is critical for accessible dermatological care but remains challenging due to computational, energy, and privacy constraints. We introduce QANA, a novel quantization-aware neuromorphic architecture for incremental skin lesion classification on resource-limited hardware. QANA effectively integrates ghost modules, efficient channel attention, and squeeze-and-excitation blocks for robust feature representation with low-latency and energy-efficient inference. Its quantization-aware head and spike-compatible transformations enable seamless conversion to spiking neural networks (SNNs) and deployment on neuromorphic platforms. Evaluation on the large-scale HAM10000 benchmark and a real-world clinical dataset shows that QANA achieves 91.6\% Top-1 accuracy and 82.4\% macro F1 on HAM10000, and 90.8\% / 81.7\% on the clinical dataset, significantly outperforming state-of-the-art CNN-to-SNN models under fair comparison. Deployed on BrainChip Akida hardware, QANA achieves 1.5\,ms inference latency and 1.7\,mJ energy per image, reducing inference latency and energy use by over 94.6\%/98.6\% compared to GPU-based CNNs surpassing state-of-the-art CNN-to-SNN conversion baselines. These results demonstrate the effectiveness of QANA for accurate, real-time, and privacy-sensitive medical analysis in edge environments.