arXiv:2507.03558v1 Announce Type: cross Abstract: Brain stroke is one of the leading causes of mortality and long-term disability worldwide, highlighting the need for precise and fast prediction techniques. Computed Tomography (CT) scan is considered one of the most effective methods for diagnosing brain strokes. The majority of stroke classification techniques rely on a single slice-level prediction mechanism, allowing the radiologist to manually choose the most critical CT slice from the original CT volume. Although clinical evaluations are often used in traditional diagnostic procedures, machine learning (ML) has opened up new avenues for improving stroke diagnosis. To supplement traditional diagnostic techniques, this study investigates the use of machine learning models, specifically concerning the prediction of brain stroke at an early stage utilizing CT scan images. In this research, we proposed a novel approach to brain stroke detection leveraging machine learning techniques, focusing on optimizing classification performance with pre-trained deep learning models and advanced optimization strategies. Pre-trained models, including DenseNet201, InceptionV3, MobileNetV2, ResNet50, and Xception, are utilized for feature extraction. Additionally, we employed feature engineering techniques, including BFO, PCA, and LDA, to enhance models' performance further. These features are subsequently classified using machine learning algorithms such as SVC, RF, XGB, DT, LR, KNN, and GNB. Our experiments demonstrate that the combination of MobileNetV2, LDA, and SVC achieved the highest classification accuracy of 97.93%, significantly outperforming other model-optimizer-classifier combinations. The results underline the effectiveness of integrating lightweight pre-trained models with robust optimization and classification techniques for brain stroke diagnosis.