本期AMA节目中，Peter深入探讨了代谢疾病这一关键话题。他首先阐述了不良代谢健康如何增加患心血管疾病、癌症、神经退行性疾病等慢性疾病的风险，以及对整体死亡率的影响。节目中，Peter详细介绍了用于评估代谢健康的各种指标和测试方法，并强调了他个人在患者身上使用的方法。最后，Peter概述了可以用来改善代谢健康的因素。节目涵盖了代谢健康的重要性、评估方法、以及干预措施，为听众提供了关于如何改善代谢健康的实用信息。

🩺 代谢健康的重要性：Peter强调了代谢健康对于整体健康至关重要，不良代谢健康会显著增加患慢性疾病的风险，如心血管疾病、癌症和神经退行性疾病。

🔬 代谢健康评估方法：节目介绍了多种评估代谢健康的方法，包括身体重量、BMI、各种血液测试、乳酸水平、Zone 2输出、心肺运动测试（CPET）、内脏脂肪、口服葡萄糖耐量测试（OGTT）、连续血糖监测（CGM）以及肝功能评估等。

😴 干预措施：Peter探讨了改善代谢健康的多种干预措施，包括睡眠、运动、饮食和减少压力。他强调这些因素对代谢健康的积极影响，并提供了实践建议。

View the Show Notes Page for This Episode

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In this “Ask Me Anything” (AMA) episode, Peter dives deep into the critical topic of metabolic disease. He first sheds light on how poor metabolic health drives up the risk of developing other chronic diseases such as cardiovascular disease, cancer, neurodegenerative disease, and overall mortality. He explores the array of metrics and tests used to assess metabolic health, underscoring his preferred methodologies utilized with patients. Finally, Peter provides an overview of the factors one can manipulate in order to improve metabolic health.

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We discuss:

Importance of metabolic health and a primer on metabolic disease [1:30]; How poor metabolic health increases one’s risk for other chronic diseases [6:00]; How useful is body weight and BMI for estimating metabolic health? [9:45]; Overview of various tests and metrics used to understand metabolic health [12:15]; Traditional biomarkers and how Peter’s point of view may differ from the guidelines [15:00]; Lactate: insights into metabolic health through fasting and resting lactate levels [17:00]; Zone 2 output: an important functional test of metabolic health [20:00]; Cardiopulmonary exercise testing (CPET) [25:45]; Visceral adipose tissue (VAT): what is VAT and how does it impact health? [27:00]; Oral glucose tolerance test (OGTT): how it works and why it is such an important metric for assessing metabolic health [32:15]; The utility of a continuous glucose monitor (CGM) [40:45]; Liver function and NAFLD [42:15]; Sleep as an intervention [46:00]; Exercise as an intervention [53:15]; Diet and nutrition [59:00]; How reducing stress can improve metabolic health [1:05:15]; and More.

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