本期播客邀请国际知名的乳腺癌专家Harold Burstein，深入探讨了乳腺癌的各个方面。内容涵盖了乳腺解剖结构、内分泌因素、癌前病变、浸润性乳腺癌等，并对各种筛查方法（如自检、钼靶、超声和MRI）进行了详细介绍。此外，节目还讨论了乳腺癌的最新治疗进展、遗传因素以及男性乳腺癌等问题，为听众提供了全面的乳腺癌知识。

🌸 乳腺癌的复杂性：Burstein医生首先阐述了乳腺的解剖结构和乳腺癌的发展的复杂因素。他还详细介绍了乳腺癌的三大主要类别。

🔎 筛查与早期检测：节目深入探讨了乳腺癌的筛查方法，包括自检、钼靶、超声和MRI等。同时，讨论了关于早期筛查和检测的争议。

💊 治疗方案与进展：Burstein医生分享了乳腺癌治疗的最新进展，包括辅助治疗和新辅助治疗。节目还讨论了激素替代疗法在乳腺癌缓解期女性中的应用。

🧬 遗传因素与男性乳腺癌：节目探讨了遗传因素在乳腺癌中的作用，并关注了相对不常见的男性乳腺癌问题，这部分内容有助于更全面地理解乳腺癌。

🏥 多学科协作的重要性：Burstein医生强调了由癌症中心提供的多学科护理的重要性，这种综合性的治疗方法能够更好地服务患者。

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Harold (Hal) Burstein is an internationally renowned breast cancer expert. In this episode, Hal discusses a broad range of topics related to breast cancer, starting with the intricacies of breast anatomy and the endocrinological factors at play. He covers the spectrum of breast cancer, from precancerous lesions to invasive breast cancer, classifying these conditions into a helpful framework. He delves into various screening methods, including self-exams, mammograms, ultrasounds, and MRIs, and addresses the ongoing debate surrounding early screening and detection. Hal provides insights into the latest advancements in cancer treatment, offering valuable guidance for individuals to understand their unique circumstances within the three primary categories of breast cancer. Finally, Hal delves into the role of genetics in breast cancer and brings attention to the less commonly addressed issue of male breast cancer.

We discuss:

The prevalence and mortality rate of breast cancer in women [4:15]; The anatomy of the breast and the complex factors behind breast cancer development [6:30]; The three main categories of breast cancer [16:45]; Breast cancer risk: the impact of menopause, estrogen, breast density, obesity, and more [21:15]; Finding and evaluating lumps in the breast [25:30]; Identifying and treating precancerous lesions like ductal carcinoma in situ (DCIS) [31:00]; Post-lumpectomy for DCIS: standard of care, future risk of cancer, and pros and cons of radiation and other preventative options [41:15]; Lobular carcinoma in situ (LCIS): how it differs from DCIS in terms of treatment and future risk of invasive cancer [55:00]; Breast cancer screening: mammography, ultrasound, MRI, and more [1:03:45]; Invasive breast cancer: pathology report, surgery, and survival [1:11:00]; The argument for aggressive screening for breast cancer [1:22:15]; Advances in the treatment of breast cancer, adjuvant therapy, and neoadjuvant therapy [1:27:00]; The use of hormone replacement therapy in women who are in remission from breast cancer [1:41:15]; The role of genetics in breast cancer [1:44:45]; The importance of multidisciplinary care delivered by cancer centers [1:53:15]; Breast cancer in men [2:03:30]; Parting thoughts and takeaways [2:05:45]; and More.

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